产品货号:
Z11705
中文名称:
ATR抗体
英文名称:
Anti-ATR Antibody
产品规格:
100μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-ATR Antibody |
指标别名 | ATR;FRAP related protein 1;FRP1;MEC1;SCKL;SCKL1 |
克隆性 | Polyclonal |
检验物种 | human |
应用范围 | WB,IHC,ELISA |
基因名称 | ATR |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | Synthesized peptide derived from human ATR around the non-phosphorylation site of S428. |
计算分子量 | 301KD |
成分 | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
纯化方式 | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | -20℃可保存1年,短期保存或频繁使用请置于4℃,可保存一个月,避免反复冻融。 |
背景资料 | Serine/threonine-protein kinase ATR also known as ataxia telangiectasia and Rad3-related protein (ATR) or FRAP-related protein 1 (FRP1) is an enzyme that,in humans,is encoded by the ATR gene.The protein encoded by this gene is a serine/threonine kinase and DNA damage sensor,activating cell cycle checkpoint signaling upon DNA stress.The encoded protein can phosphorylate and activate several proteins involved in the inhibition of DNA replication and mitosis,and can promote DNA repair,recombination,and apoptosis.This protein is also important for fragile site stability and centrosome duplication.Defects in this gene are a cause of Seckel syndrome 1. |
Uniprot ID | Q13535 |
基因名全称 | Serine/threonine-protein kinase ATR |
蛋白名全称 | Serine/threonine-protein kinase ATR |
推荐稀释比 | WB 1:500~1:2000 IHC 1:100~1:300 ELISA 1:40000 |
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